There is no doubt Werdum will submit cain if cain decides to grapple with him.
If dos santos wasn't such a novice on the ground he could have submitted too on multiple occasions.
Cain has yet to face a good submission grappler and werdum is the best grappler in the world at HW.
Cain's best strategy against werdum
Would be to avoid the ground like the plague and simply try and outstrike werdum standing up. 
Isn't JDS a blackbelt? Cain is gonna walk through Werdum, especially since Werdum hasn't fought in a long time 
Cain KO's Werdum in the second or third.
"Cain has yet to face a good submission grappler and werdum is the best grappler in the world at HW."
He fought big nog and knocked him the eff out!
Cain is great but he gets hit in the face way to much and that is a dangerous weakness as a heavyweight. His cardio is off the charts.
Kinda hard to submit Cain when he's covered in his opponents blood.
The same would happen to Werdum and he can then blame it on all the blood like Bigfoot did.
FONS - Cain is great but he gets hit in the face way to much and that is a dangerous weakness as a heavyweight. His cardio is off the charts.
Roll with the punches. Roll with the punches.
IAmNotImpressedbyYourStocktonSlap -FONS - Cain is great but he gets hit in the face way to much and that is a dangerous weakness as a heavyweight. His cardio is off the charts.Roll with the punches. Roll with the punches.
This ^
MMAjustice - "Cain has yet to face a good submission grappler and werdum is the best grappler in the world at HW."
He fought big nog and knocked him the eff out!
And Werdum submitted Nog.