Most Season-Ending Injuries in One Football Game?

A buddy and I were talking about this. We couldn't agree on it, and Googling didn't help.

Any idea what's the largest number of season-ending injuries in one football game, pro or college? How about the most career ending injuries in one game?

I know a game @ Veterans a Stadium claimed a bunch of players once. And in a preseason game or at least early in the regular season the AZ Cardinals came to MN and lost like 5 starters for the season- Their season was done Phone Post 3.0