Hard to believe he's a 4 to 1 underdog. Cain has had a long layoff and no doubt ring rust will play a factor.
We all saw what happened the last time he had a long layoff.
Couple that with the fact that Werdum has looked to be in his prime recently and really hitting his stride.
Werdum also will have the crowd advantage being as he can communicate with them in Spanish.
I can easily see Werdum winning by 1st or 2nd round submission and wouldn't be shocked at all if he won by TKO. 
I have a 3 fight parlay of werdum, lawler, romero.
15 wins 375 
Cain will run through werdum
Someonestolemysocks - I have a 3 fight parlay of werdum, lawler, romero.You have a very good chance of winning that.
15 wins 375
Lawler should be the favorite. I have no idea why he's an underdog.
Romero is a beast and will decimate Jacare.
Obviously Wedum/Cain will be the closest fight but I really think Werdum will surprise him
teamquestnorth -Romero is fighting machidaSomeonestolemysocks - I have a 3 fight parlay of werdum, lawler, romero.You have a very good chance of winning that.
15 wins 375
Lawler should be the favorite. I have no idea why he's an underdog.
Romero is a beast and will decimate Jacare.
Obviously Wedum/Cain will be the closest fight but I really think Werdum will surprise him
I picked him because over machida because I think machidas back too quick after the beating he took.
teamquestnorth -Romero will not decimate jacare, jacare will hand Romero his ass..Someonestolemysocks - I have a 3 fight parlay of werdum, lawler, romero.You have a very good chance of winning that.
15 wins 375
Lawler should be the favorite. I have no idea why he's an underdog.
Romero is a beast and will decimate Jacare.
Obviously Wedum/Cain will be the closest fight but I really think Werdum will surprise him
I do think werdum will win tho. Hoping anyways.
I will be betting on Werdum.
Man, looking forward to this fight, but the rest of the card is weak. Alvarez vs Melendez is good. The other fights are not PPV quality IMO.
Still, nothing quite like a HW fight when it's two of the greatest of all time. Both in their prime.
I'm definitely picking werdum
Lots of strong opinions and very little factual knowledge here
Werdum wins. No epo, no chance.
Werdum is a live dog