The timing wouldn't have mattered for shit if Chuck's hands were up when he was throwing.
The timing was perfect... but it could've easily been thwarted by a simple difference of hand/arm positioning on Chuck's part.
Sad.
Chuck is right. It's not as if he was being battered around the ring like an over-the-hill Muhammed Ali against Holmes. He got caught by a KO punch. It can happen to anybody. Next time he should keep that other hand up.